Article Correctness Is Author's Responsibility: Complete chromosome 8 sequence reveals novel genes and disease risks

(University of Washington School of Medicine/UW Medicine) A full assembly of human chromosome 8 has now been completed. Its DNA content and arrangement are of interest in primate and human evolution, in several immune and developmental disorders, and in chromosome sequence structure and function generally. This chromosome has a fast-evolving region with a highly accelerated mutation rate in humans and human-like species. Also, comparative studies with ape and macaque sequences are helping to chart the evolutionary history of the chromosome 8 centromere.