This Medical News feature provides highlights of a comprehensive international database that can help clinicians and patients clarify the meaning of BRCA1 and BRCA2 genetic variants.

Patients with rheumatoid arthritis who take 10 mg of tofacitinib twice a day are at increased risk of dying or developing blood clots in the lungs compared with patients who take 5 mg twice a day, the FDA has warned.

The FDA has added a boxed warning to the gout medication febuxostat cautioning that the drug may increase the risk of death from heart-related causes or any cause compared with another gout drug, allopurinol. The finding is from a large postmarketing s…

A new task force comprising experts from the FDA, Centers for Disease Control and Prevention (CDC), and the Centers for Medicare & Medicaid Services (CMS) will work with clinical and public health laboratories to facilitate their use of diagnostic …

This Medical News & Perspectives article describes a report showing that the prevalence of atopic eczema rebounds in older adults.

The FDA has approved the first test designed to help diagnose a sexually transmitted infection caused by the Mycoplasma genitalium bacterium.

During 2018 the FDA approved 106 novel devices, surpassing the 40-year record it set in 2017 by approving 99 novel devices.

The first generic version of vigabatrin has received FDA approval for treating complex partial seizures.

Clinicians can use a recently approved mobile medical app to help patients with opioid use disorder stay in their outpatient treatment program.

The FDA has approved a once-daily oral treatment for adults with chronic idiopathic constipation. Prucalopride is a selective serotonin-4 (5HT4) receptor agonist that enhances colonic peristalsis to increase bowel motility. The drug has been approved f…